http://healthland.time.com/2010/01/20/r ... -drinking/The study’s authors hypothesize that the alcohol intolerance associated with facial flushing may have evolved as a survival strategy enabling ancient populations to enjoy the positive effects of alcohol derived from fermented rice — it can be used as a disinfectant and preservative — while imbibing in moderation.
Drinking responsibly, so far, has nothing to do with genes. It is about socialized behaviors, learning right from wrong.