Too much testosterone kills brain cells !!!!!!!
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This General Forum is for general discussions from daily chitchat to more serious discussions among Somalinet Forums members. Please do not use it as your Personal Message center (PM). If you want to contact a particular person or a group of people, please use the PM feature. If you want to contact the moderators, pls PM them. If you insist leaving a public message for the mods or other members, it will be deleted.
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Too much testosterone kills brain cells !!!!!!!
POSTED: 1942 GMT (0342 HKT), September 28, 2006
......."Next time a muscle-bound guy in a sports car cuts you off on the highway, don't get mad -- just take a deep breath and realize that it might not be his fault,"
WASHINGTON (Reuters) -- Too much testosterone can kill brain cells, researchers say, in a finding that may help explain why steroid abuse can cause behavior changes such as aggressiveness and suicidal tendencies.
Tests on brain cells in lab dishes showed that while a little of the male hormone is good, too much of it causes cells to self-destruct in a process similar to that seen in brain illnesses such as Alzheimer's.
"Too little testosterone is bad, too much is bad but the right amount is perfect," said Barbara Ehrlich of Yale University in Connecticut, who led the study.
Testosterone is key to the development, differentiation and growth of cells and is produced by both men and women, although men produce about 20 times more of the hormone.
It can also be abused, and recent scandals have involved athletes who use the hormone, or steroids that turn into testosterone in the body, for an unfair advantage.
"Other people have shown that high levels of steroid can cause behavioral changes," Ehrlich said in a telephone interview.
"We can show that when you have high levels of steroids, you have high testosterone and that can destroy the nerve cells. We know that when you lose brain cells you lose function."
Ehrlich's team tried the same thing with the "female" hormone estrogen, just to be fair.
"We were surprised, but it actually looks like estrogen is neuroprotective. If anything, there is less cell death in the presence of estrogen," she said.
Writing in the Journal of Biological Chemistry, Ehrlich and colleagues said their findings meant people should think twice about supplementing with testosterone, even if it does build muscle mass and aid recovery after exercise.
"These effects of testosterone on neurons will have long-term effects on brain function," they wrote.
"Next time a muscle-bound guy in a sports car cuts you off on the highway, don't get mad -- just take a deep breath and realize that it might not be his fault," Ehrlich said in a statement.
The cells die via a process called apoptosis, also known as cell suicide or programmed cell death.
"Apoptosis is an important thing for the brain -- the brain needs to weed out some of the cells. But when it happens too frequently, you lose too many cells and causes problems."
A similar process is seen in Alzheimer's disease, the most common cause of dementia in the United States, affecting an estimated 4.5 million Americans, and Huntington's disease, another fatal brain illness.
"Our results suggest that the responses to elevated testosterone can be compared with these pathophysiological conditions," the researchers wrote.
Copyright 2006 Reuters. All rights reserved.This material may not be published, broadcast, rewritten, or redistributed.
......."Next time a muscle-bound guy in a sports car cuts you off on the highway, don't get mad -- just take a deep breath and realize that it might not be his fault,"
WASHINGTON (Reuters) -- Too much testosterone can kill brain cells, researchers say, in a finding that may help explain why steroid abuse can cause behavior changes such as aggressiveness and suicidal tendencies.
Tests on brain cells in lab dishes showed that while a little of the male hormone is good, too much of it causes cells to self-destruct in a process similar to that seen in brain illnesses such as Alzheimer's.
"Too little testosterone is bad, too much is bad but the right amount is perfect," said Barbara Ehrlich of Yale University in Connecticut, who led the study.
Testosterone is key to the development, differentiation and growth of cells and is produced by both men and women, although men produce about 20 times more of the hormone.
It can also be abused, and recent scandals have involved athletes who use the hormone, or steroids that turn into testosterone in the body, for an unfair advantage.
"Other people have shown that high levels of steroid can cause behavioral changes," Ehrlich said in a telephone interview.
"We can show that when you have high levels of steroids, you have high testosterone and that can destroy the nerve cells. We know that when you lose brain cells you lose function."
Ehrlich's team tried the same thing with the "female" hormone estrogen, just to be fair.
"We were surprised, but it actually looks like estrogen is neuroprotective. If anything, there is less cell death in the presence of estrogen," she said.
Writing in the Journal of Biological Chemistry, Ehrlich and colleagues said their findings meant people should think twice about supplementing with testosterone, even if it does build muscle mass and aid recovery after exercise.
"These effects of testosterone on neurons will have long-term effects on brain function," they wrote.
"Next time a muscle-bound guy in a sports car cuts you off on the highway, don't get mad -- just take a deep breath and realize that it might not be his fault," Ehrlich said in a statement.
The cells die via a process called apoptosis, also known as cell suicide or programmed cell death.
"Apoptosis is an important thing for the brain -- the brain needs to weed out some of the cells. But when it happens too frequently, you lose too many cells and causes problems."
A similar process is seen in Alzheimer's disease, the most common cause of dementia in the United States, affecting an estimated 4.5 million Americans, and Huntington's disease, another fatal brain illness.
"Our results suggest that the responses to elevated testosterone can be compared with these pathophysiological conditions," the researchers wrote.
Copyright 2006 Reuters. All rights reserved.This material may not be published, broadcast, rewritten, or redistributed.
- Basra-
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I was talking about the same thing today -didn't I??

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I personally think they should have women be leaders of Somalia.CNN ceo & founder Ted--said---throughout centuries men ruled the world & are responsible for the wars & chaos that is going on currently.Women are naturally nurturing & thus would build a country, nurture & not destroy.Men are biologically disposed to aggression & pulling muscles & prooving their pathetic masculinity towards fellow men while women---although cunningly gossipy about each other, are far more gentle & smart thinking.Men biologically loose brain cells everytime they are mad or are excited during the act ' of ----you know what. In fact---statistic have proven the more a man has a larger quotent of Testosterone ---the more the man is incapable of using his brain & is driven by whimsy impulsive actions.In other words--men with high concetration of Testosterone are thus..... dumber! But unfortunately the men with less Testosterone tend to end up being little fairies & thus bring another total separate catastrophe dilemma. But one problem is worst than the other, naturally we dont want wars & blood everywhere. Therefore the ideal man should have a reasonable 'balanced' concetration of testosterones & certainly posses a good deal of education in his manly grip.
This fanatic Islamic government is certainly better than the uncertainty of moryaan ruling & thug endeavors but it is not the 'ideal' answer for Somalia.You cannot mix religion & state together.Religion is solely supposed to inspire you to be without agenda, total devotion to Allah--your supreme maker. A muslim is supposed to be strictly worshiping Allah & not worshing ---power, greed & governing, thus my reason to say it should always be separate. "



'
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I personally think they should have women be leaders of Somalia.CNN ceo & founder Ted--said---throughout centuries men ruled the world & are responsible for the wars & chaos that is going on currently.Women are naturally nurturing & thus would build a country, nurture & not destroy.Men are biologically disposed to aggression & pulling muscles & prooving their pathetic masculinity towards fellow men while women---although cunningly gossipy about each other, are far more gentle & smart thinking.Men biologically loose brain cells everytime they are mad or are excited during the act ' of ----you know what. In fact---statistic have proven the more a man has a larger quotent of Testosterone ---the more the man is incapable of using his brain & is driven by whimsy impulsive actions.In other words--men with high concetration of Testosterone are thus..... dumber! But unfortunately the men with less Testosterone tend to end up being little fairies & thus bring another total separate catastrophe dilemma. But one problem is worst than the other, naturally we dont want wars & blood everywhere. Therefore the ideal man should have a reasonable 'balanced' concetration of testosterones & certainly posses a good deal of education in his manly grip.
This fanatic Islamic government is certainly better than the uncertainty of moryaan ruling & thug endeavors but it is not the 'ideal' answer for Somalia.You cannot mix religion & state together.Religion is solely supposed to inspire you to be without agenda, total devotion to Allah--your supreme maker. A muslim is supposed to be strictly worshiping Allah & not worshing ---power, greed & governing, thus my reason to say it should always be separate. "
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- SomaliNet Super
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Basra,
I am AFRAID that u did'nt GET the POINT of the TOPIC. It doest't go about the NORMAL testestrone but about the ADDITIONAL or SUPPELMENTARY one that is tAKEN by BODYBUILDERS etc.
The NORMAL testestrone is herby DECLARED as INNOCENT.
....... I am the MASTER of my chest; i am the CAPTAIN of my fist....
Ur Fellow daanyeer with Intellectual Glasses In S'net !!!!!!!!!!!!!!
YYY Col\Prof Daanyeer YYY
I am AFRAID that u did'nt GET the POINT of the TOPIC. It doest't go about the NORMAL testestrone but about the ADDITIONAL or SUPPELMENTARY one that is tAKEN by BODYBUILDERS etc.
The NORMAL testestrone is herby DECLARED as INNOCENT.
....... I am the MASTER of my chest; i am the CAPTAIN of my fist....
Ur Fellow daanyeer with Intellectual Glasses In S'net !!!!!!!!!!!!!!
YYY Col\Prof Daanyeer YYY
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- SomaliNet Super
- Posts: 15780
- Joined: Tue Aug 12, 2003 7:00 pm
- Location: Beer moos ku yaallo .biyuhuna u muuqdaan
[quote="gurey25"]what about estrogen?[/quote]
That is what makes MATUE MAN DISCUSS about weigtlossing, YOGA, OPRAH, BEUTY&BOLD, DESPERATE HOUSEWIVES etc.
....... I am the MASTER of my chest; i am the CAPTAIN of my fist....
Ur Brother with Intellectual Glasses In S'net !!!!!!!!!!!!!!
YYY Col\Prof Daanyeer YYY
That is what makes MATUE MAN DISCUSS about weigtlossing, YOGA, OPRAH, BEUTY&BOLD, DESPERATE HOUSEWIVES etc.
....... I am the MASTER of my chest; i am the CAPTAIN of my fist....
Ur Brother with Intellectual Glasses In S'net !!!!!!!!!!!!!!
YYY Col\Prof Daanyeer YYY
[quote="Daanyeer"][quote="gurey25"]what about estrogen?[/quote]
That is what makes MATUE MAN DISCUSS about weigtlossing, YOGA, OPRAH, BEUTY&BOLD, DESPERATE HOUSEWIVES etc.
....... I am the MASTER of my chest; i am the CAPTAIN of my fist....
Ur Brother with Intellectual Glasses In S'net !!!!!!!!!!!!!!
YYY Col\Prof Daanyeer YYY[/quote]

That is what makes MATUE MAN DISCUSS about weigtlossing, YOGA, OPRAH, BEUTY&BOLD, DESPERATE HOUSEWIVES etc.
....... I am the MASTER of my chest; i am the CAPTAIN of my fist....
Ur Brother with Intellectual Glasses In S'net !!!!!!!!!!!!!!
YYY Col\Prof Daanyeer YYY[/quote]






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- Basra-
- SomaliNet Super
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[quote="gurey25"]Hey you have to explore your femenin side once in a while.
by the way i hate Bold and Beautifull, all Soap operas
and i do not watch oprah or any talk show.[/quote]
Sure...
Gurey you--dont! You are Exhibit A for less Testosterones & more estrogen in the system & Who turned--u know --what.
Cawar@lol
U are right--as long as you can do the thang--God Forbid we can't have man ---scuk at one THING they are actually good at.
(No need to get into specifics. lol)
Danyeer--I KNOW what the article implied. Although its emphasis was on steroids & the affect of additional Testosterone in the system-- but what i was attempting is my own hypothesis-- i was thinking abstractly here as any intellectual would-- these findings paint a clear picture of the 'side effects' of heavy dose of Testosterones in the system.And consequently on men in general, whose aggressiveness is responsible for the war going on in the world.I was stating that if such excessive steroids causing Testosterones hormones could affect brain cells--well this clearly says--men should be studied.Maybe its not their fault that they are aggressive brutes who beat their chests like gorrilla marking their territory. This is evidently a biological factor.
Danyeer unlike you-- i think with my brains. I am not Robotic like you-- who doesn't have independent thoughts other than quoting studies, articles & etc etc -----let us hear your opinions once in a while---so we may delightfully evaluate & judge your psychic!! ( I am fully aware of your handicap:Your English is CRAP. You use off Somali vernacular in your writing that makes me cringe. Practice on your English dear- IF drunk Qudhac can manage his screwed up grammar somehow--so can you dear.
)

by the way i hate Bold and Beautifull, all Soap operas
and i do not watch oprah or any talk show.[/quote]
Sure...




Cawar@lol
U are right--as long as you can do the thang--God Forbid we can't have man ---scuk at one THING they are actually good at.



Danyeer--I KNOW what the article implied. Although its emphasis was on steroids & the affect of additional Testosterone in the system-- but what i was attempting is my own hypothesis-- i was thinking abstractly here as any intellectual would-- these findings paint a clear picture of the 'side effects' of heavy dose of Testosterones in the system.And consequently on men in general, whose aggressiveness is responsible for the war going on in the world.I was stating that if such excessive steroids causing Testosterones hormones could affect brain cells--well this clearly says--men should be studied.Maybe its not their fault that they are aggressive brutes who beat their chests like gorrilla marking their territory. This is evidently a biological factor.

Danyeer unlike you-- i think with my brains. I am not Robotic like you-- who doesn't have independent thoughts other than quoting studies, articles & etc etc -----let us hear your opinions once in a while---so we may delightfully evaluate & judge your psychic!! ( I am fully aware of your handicap:Your English is CRAP. You use off Somali vernacular in your writing that makes me cringe. Practice on your English dear- IF drunk Qudhac can manage his screwed up grammar somehow--so can you dear.





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